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What is HGH and how is it related to longevity?
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Human growth hormone is produced in the anterior portion of the pituitary gland, a pea-sized organ suspended just below the brain, which produces no fewer than nine different hormones. Between them these hormones regulate a number of essential physiological functions, including water and energy balance, reproductive activity and the workings of many other glands in the body. Growth hormone is a powerful anabolic hormone that occurs naturally in the human body. It is produced by the pituitary gland in the brain and stimulates the growth of muscle, cartilage, and bone. It is made throughout a person's lifetime but is more plentiful during youth. It stimulates growth in children and plays an important role in adult metabolism. Scientists first isolated HGH in 1956. Three years later, NHS doctors began to use it in the treatment of children suffering from stunted growth. Before the advent of genetic engineering, the only source of HGH was human corpses. The pituitary glands were removed from cadavers, processed and the hormones made available in injectable form. Synthetic HGH can now be made in unlimited quantities in the laboratory.
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In laymans terms, Human Growth Hormone or HGH is a hormone produced by the pituitary gland (master gland which promotes linear growth). The pituitary gland is located in your head, below your brain. HGH production occurs largely in our youth, coming to a peak in our 20's. After our 20's, a slow decline of HGH production naturally occurs. Generally speaking, by the time we reach and pass the age of 40, our bodies are producing sub-optimal amounts of HGH.
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Why HGH is required in our body?
Human growth hormone, also called somatotropin, is a protein hormone of 190 amino acids (building blocks of protein) that is created and secreted by the anterior pituitary gland. It has two types of effects, both of which are highly beneficial to the vital, active human body. One main type of action of the HGH is its direct effects on other kinds of cells. The growth hormone binds to its receptor on target cells, then creates some particular action. Fat cells, for example, are the target cells of HGH, so they have growth hormone receptors. Once bonded there, the growth hormone causes them to break down triglyceride and suppresses their ability to take up and accumulate circulating lipids -- in other words, fat storage is prevented! HGH also acts to create other indirect effects in the body by causing secretion of IGF-1, an insulin-like growth factor hormone. IGF-1 is secreted from the liver and other tissues in response to growth hormone. This is the action that governs mostly growth-related effects of HGH.
This same effect is also the power behind muscle growth. It stimulates both the differentiation and proliferation of muscle cells, stimulates amino acid uptake and synthesizes protein in muscle and other tissues. This is where HGH's ability to influence overall muscle and skin tone comes from. Because of the abilities of HGH mentioned above, you can soon see that without it, muscle tone declines, fat stubbornly sits in the body and resists metabolism, and hair, skin and nails (all composed of proteins) deteriorate. In fact, scientists now believe that HGH has a role in most healthy functions of the body, including sexual function, proper operation of stomach and bowels, liver, and all glandular systems.
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Better body contour - HGH may be the most effective fat-loss regimen ever discovered. Raised levels of HGH can re-contour the body, melting away fat and building muscle. In two studies performed by Dr. David Clemmons, chief of endocrinology at the University of North Carolina in Chapel Hill, elevated HGH levels combined with dieting caused a 25% acceleration in the rate of fat loss, above and beyond the effect of dieting alone. In 11 weeks, the subjects lost between 20 to 32 pounds of fat while maintaining their body tone.
In 1985, Keith Kelley, M.D., a research immunologist at the University of Illinois at Urbana-Champaign, found that elevated levels of HGH could regenerate a shriveled thymus gland. This improves the manufacturing of new antibodies and increases the production of white blood cells.
According to Dr. Ronald Klatz and Dr. Robert Goldman of the American Academy fo Anti-Aging Medicine, HGH can "reduce body fat by 14.4 percent after six months, without dieting." Increased Muscle Mass - Dr. Klatz and Dr. Goldman as stating HGH causes "an average gain of 8.8 percent in muscle mass after six months, without excercise."
Heart failure reversal - In a 1996 study in the New England Journal of Medicine, HGH was given to seven patients - five men and two women with moderate to severe heart failure. They experienced increased thickness of the left ventricular wall, an enhancement in the ability of the heart to contract and pump blood, reduced oxygen requirement of the heart, improved exercise capacity and an enhanced quality of life.
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Testimonials - longevity
"I must say that I have been extremely happy with the results of HGH. There hasn't been anything that would make my skin look better. Now I am free from acne and my blemish actually faded. Thank you again." - Randy, Los Angeles, CA
"As a life long athlete, I appreciate the knowledge and HGH products that I have received from you. I do believe that HGH therapy is an important part of my growing older, so I'm glad to have found your website because of the quality and affordability of your HGH products." - Doug Stratton
"It was with great nterest that I read your site pertaining to the above subject matter. No one knows what it is like to be HGH deficient. It robs you of life itself. Thank God they where finally able to diagnosis me last year as being HGH deficient. This was done through the Director of Endocrinology at New England Medical Center in Boston, Massachusetts. Argenine testing came up with a constant 50 reading for IGF-1. I have been on Humatrope nightly injections for one year as of the 15th of this month. Even after one year and constant increasing of IU'S the level is still only 135 but the results have been short of miraculous. Everything I have seen written on your web site is true. I truly believe that this problem exists on a far more reaching level then the Medical Community believes." - Thomas J. Malley
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